Results 171 to 180 of about 36,759 (336)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

A robust edge-detection approach for precise delineation of deep structures from potential field data: Structural insights supported by remote sensing. [PDF]

Sci Rep
Eldosouky AM, Saada SA, Allam SA, El-Gawad AA, Henaish A, Zamzam S.   +5 more
europepmc   +1 more source

Tectonic analysis of Baja California and Parras shear belt in Mexico [PDF]

The author has identified the following significant results. Geological correlation of terrain across the Gulf of California using ERTS-1 imagery revealed significant similarities between Isla Tiburon, Isla Angel de la Guarda, and the San Carlos Range in
Abdel-Gawad, M., Tubbesing, L.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Deciphering aeromagnetic data for sustainable sedimentary and structural insights in Obudu Plateau, Ikom Mamfe embayment and Oban Massif, southeastern Nigeria. [PDF]

Sci Rep
Eze OE, Ekwok SE, Thompson CE, Odey EI, Okiwelu AA, Abdelrahman K, Fnais MS, Andráš P, Eldosouky AM.   +8 more
europepmc   +1 more source

Investigations using data in Alabama from ERTS-A [PDF]

There are no author-identified significant results in this ...
Henry, H. R., Whittle, G. P.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structures control gold mineralization in the western Allaqi shear belt of Egypt from high-precision geophysical and remote sensing datasets. [PDF]

Sci Rep
Eldosouky AM, El-Wahed MAA, El Monsef MA, Attia M.   +3 more
europepmc   +1 more source

Structural geologic analysis of Nevada using ERTS-1 images: A preliminary report [PDF]

Structural analysis of Nevada using ERTS-1 images showns several previously unrecognized lineaments which may be the surface manifestations of major fault or fracture zones. Principle trends are NE, NW, NNE-NNW, and ENE.
Rowan, L. C., Wetlaufer, P. H.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source