Smoothing properties in multistep backward difference method and time derivative approximation for linear parabolic equations [PDF]
Yubin Yan
openalex +1 more source
Efficient Inference in First Passage Time Models. [PDF]
Liu S, Fengler A, Frank MJ, Harrison MT.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Application of randomized quadrature formulas to the finite element method for elliptic equations. [PDF]
Kruse R, Polydorides N, Wu Y.
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Beyond linearity - a new Partial Least Squares - Path Modelling (PLS-PM) inner weighting scheme for detecting and approximating nonlinear structural relationships in Structural Equation Models. [PDF]
Mendes JM, Coelho PS.
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Two-Temperature and Thermal Plasma Kinetic Theories. [PDF]
Giovangigli V.
europepmc +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Linear Approximations of Power Flow Equations in Electrical Power System Modelling—A Review of Methods and Their Applications [PDF]
Paweł Pijarski +4 more
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