Results 161 to 170 of about 77,454 (294)

Reflection on "Site-specific PEGylation of proteins by a Staudinger-phosphite reaction": from protein modification to ADCs in the clinic. [PDF]

Chem Sci
Schuppe KT, Hackenberger CPR.
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Radical-to-radical push-pull effect enhances single-molecule conductance in asymmetric diradicals. [PDF]

Chem Sci
Dai D, Zhan Q, Shi T, Liu X, Chen L, Quintero SM, Wang D, Casado J, Zheng Y.   +8 more
europepmc   +1 more source

Effect of benzocyclobutadieno-annelation on cyclic conjugation

, 2011
670-673By extensive numerical testing it is found that two regularities for the effect of benzocyclobutadieno (BCBD) annelation on the π-electron conjugation pattern, namely, linear BCBD-annelation increases, whereas angular BCBD-annelation decreases ...
Gutman, Ivan
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Tandem Oligonucleotide Synthesis Enabled by a Reducible Linker. [PDF]

Chembiochem
Sham AH, Zakaria E, Horton NG, O'Flaherty DK.   +3 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Optimization of PEF combined microwave glycation and comparison with conventional microwave treatment for soy protein and kappa carrageenan conjugation. [PDF]

Sci Rep
Pandey N, Upadhyay A, Kumar N, Mishra S, Sinha SS.   +4 more
europepmc   +1 more source

Theoretical problems of Higgs-boson physics at the next linear collider

, 1993
We discuss some theoretical aspects of standard-model (SM) Higgs-boson (H) phenomenology at the next e"+e"- linear collider (NLC) with 300 GeV<or#approx##sq root#s<or#approx#500 GeV.
Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany), Kniehl, B.A. (Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik)   +1 more
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source