Results 41 to 50 of about 1,852 (206)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Asymptotic iteration method for solving Hahn difference equations

Advances in Difference Equations, 2021
Hahn’s difference operator D q ; w f ( x ) = ( f ( q x + w ) − f ( x ) ) / ( ( q − 1 ) x + w ) $D_{q;w}f(x) =({f(qx+w)-f(x)})/({(q-1)x+w})$ , q ∈ ( 0 , 1 ) $q\in (0,1)$ , w > 0 $w>0$ , x ≠ w / ( 1 − q ) $x\neq w/(1-q)$ is used to unify the recently ...
Lucas MacQuarrie, Nasser Saad, Md. Shafiqul Islam   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Reducibility and Stability Results for Linear System of Difference Equations

Advances in Difference Equations, 2008
We first give a theorem on the reducibility of linear system of difference equations of the form x(n+1)=A(n)x(n). Next, by the means of Floquet theory, we obtain some stability results.
Adil Misir, Aydin Tiryaki
doaj   +2 more sources

Stability for Linear Volterra Difference Equations in Banach Spaces

Abstract and Applied Analysis, 2018
This paper is devoted to studying the existence and stability of implicit Volterra difference equations in Banach spaces. The proofs of our results are carried out by using an appropriate extension of the freezing method to Volterra difference equations ...
Rigoberto Medina
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

On Growth of Meromorphic Solutions for Linear Difference Equations

Abstract and Applied Analysis, 2013
We mainly study growth of linear difference equations and where are polynomials such that and give the most weak condition to guarantee that orders of all transcendental meromorphic solutions of the above equations are greater than or equal to 1.
Zong-Xuan Chen, Kwang Ho Shon
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Perron-Type Criterion for Linear Difference Equations with Distributed Delay

Discrete Dynamics in Nature and Society, 2007
It is shown that if a linear difference equation with distributed delay of the form Δx(n)=∑k=−d0Δkζ(n+1,k−1)x(n+k−1), n≥1, satisfies a Perron condition then its trivial solution is uniformly asymptotically stable.
Jehad O. Alzabut, Thabet Abdeljawad
doaj   +1 more source