Results 91 to 100 of about 799,624 (312)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Algebra of Linear Partial Difference Operators and Its Applications [PDF]
SIAM Journal on Mathematical Analysis, 1980 The algebra of linear partial difference operators is investigated, and an elimination procedure demonstrated. Applications to combinatorics are given. In particular, a new proof and a q-analogue of MacMahon’s Master Theorem are given.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Use of identity of A. Hurwitz for construction of a linear positive operator of approximation
Journal of Numerical Analysis and Approximation Theory, 2002 By using a general algebraic identity of Adolf Hurwitz [1], which generalizes an important identity of Abel, we construct a new operator \(S_m^{(\beta_1,\ldots,\beta_m)}\) approximating the functions. A special case of this is the operator \(Q_m^\beta\)
Dimitrie D. Stancu
doaj +2 more sources
Oscillatory behavior of half-linear third order delay difference equations with non canonical operators [PDF]
, 2022 M. Nazreen Banu, S. Mehar Banu
openalex +1 more source
Spectral Radii of Bounded Operators on Topological Vector Spaces [PDF]
, 2000 In this paper we develop a version of spectral theory for bounded linear operators on topological vector spaces. We show that the Gelfand formula for spectral radius and Neumann series can still be naturally interpreted for operators on topological ...
Troitsky, Vladimir G.
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Non-degeneracy and uniqueness of periodic solutions for a Liénard equation with a linear difference operator [PDF]
, 2023 Zhibo Cheng, Yafei Li
openalex +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source