Results 91 to 100 of about 554,029 (314)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Solution Estimates for the Discrete Lyapunov Equation in a Hilbert Space and Applications to Difference Equations

open access: yesAxioms, 2019
The paper is devoted to the discrete Lyapunov equation X − A * X A = C , where A and C are given operators in a Hilbert space H and X should be found.
Michael Gil’
doaj   +1 more source

The Abel-Zeilberger Algorithm [PDF]

open access: yes, 2011
We use both Abel's lemma on summation by parts and Zeilberger's algorithm to find recurrence relations for definite summations. The role of Abel's lemma can be extended to the case of linear difference operators with polynomial coefficients.
Chen, William Y. C.   +2 more
core  

Non-Linear Structure-Aware Image Sharpening with Difference of Smoothing Operators

open access: yesFrontiers in ICT, 2015
In this paper, we propose an effective data-adaptive filtering mechanism for sharpening of noisy and moderately blurred images. We establish the connection of our proposed data-adaptive filtering procedure with the classic Difference of Gaussians (DoG ...
A. Kheradmand, P. Milanfar
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Parametric identification of Cauchy problem for one fractional differential equation

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2012
The method for parametric identification of Cauchy problem for a fractional differential equation with fractional differential operator of α ∈ (0, 1) degree according to instantaneous values of experimental observations is suggested.
Anna S Ovsienko
doaj  

On difference of operators with different basis functions

open access: yesFilomat, 2019
In the recent years several researchers have studied problems concerning the difference of two linear positive operators, but all the available literature on this topic is for operators having same basis functions.
Vijay Gupta, Ana Acu Maria
semanticscholar   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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