Results 101 to 110 of about 554,029 (314)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Homogeneous difference schemes for the coupled problems of hydrodynamics and elasticity
Учёные записки Казанского университета: Серия Физико-математические науки, 2019 Finite-difference approximations of elastic forces on the staggered moving grid were constructed. For the displacement vectors at the irregular grids in which topological and geometrical structures are subjected to minimal reasonable restrictions, with ...
I.P. Tsygvintsev +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
, 2014 The staggered-grid finite-difference (FD) method is widely used in numerical simulation of the wave equation. With stability conditions, grid dispersion often exists because of the discretization of the time and the spatial derivatives in thewave ...
Yanfei Wang +5 more
semanticscholar +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Rational analogues of Bernstein–Szabados operators on several intervals
Қарағанды университетінің хабаршысы. Математика сериясыBernstein polynomials play a very important role in approximation theory, probability theory, computer aided geometric design and many other areas. In 2017 J.
A.L. Lukashov
doaj +1 more source
Quantum response theory for nonequilibrium steady states
Physical Review Research, 2019 Quantum response theory is a cornerstone of statistical physics. However, the standard Kubo formalism is restricted to isolated equilibrium systems. We here generalize Kubo's results to open quantum systems in nonequilibrium steady states.
Michael Konopik, Eric Lutz
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Property EA and Local Spectral Theory
International Journal of Mathematics and Mathematical SciencesIn this paper, we introduce and study the spectral property EA. This property means that the difference between the approximate point spectrum and the upper semi-Fredholm spectrum coincides with the difference between the approximate point spectrum and ...
Elvis Aponte +2 more
doaj +1 more source