Results 111 to 120 of about 2,090,917 (350)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Adjoint systems and Green functionals for second-order linear integro-differential equations with nonlocal conditions

open access: yesElectronic Journal of Differential Equations, 2015
In this work, we generalize so called Green's functional concept in literature to second-order linear integro-differential equation with nonlocal conditions. According to this technique, a linear completely nonhomogeneous nonlocal problem for a second-
Ali Sirma
doaj  

On a linear system of differential equations

open access: yesJournal of Mathematics, Mechanics and Computer Science, 2019
The linear systems of partial differential equations of the first order with the identical main partsis considered. Аpplying the well-known relation between a normal system of ordinary differentialequations and a linear system of partial differential equations of the first order with the samemain parts, the existence of integral basis of a linear ...
M. M. Aldazharova, T. М. Aldibekov
openaire   +4 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Chandrasekhar equations for infinite dimensional systems [PDF]

open access: yes
Chandrasekhar equations are derived for linear time invariant systems defined on Hilbert spaces using a functional analytic technique. An important consequence of this is that the solution to the evolutional Riccati equation is strongly differentiable in
Ito, K., Powers, R. K.
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Development of identification methods for fractional differential equations with riemann-liouville fractional derivative

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2014
The methods for parametric identification of fractional differential operators with $\alpha \on (1, 2)$ degree according to instantaneous values of experimental observations based on the Barrett differential equation example are suggested. The methods are
Anna S Ovsienko
doaj   +1 more source

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