Results 121 to 130 of about 2,090,917 (350)
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Asymptotic solutions of certain linear differential equations in which the coefficient of the parameter may have a zero [PDF]
, 1936 Henry Scheffé
openalex +1 more source
On Linear Differential Equations
Transactions of the Philosophical Society of Queensland(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
On linear matrix differential equations
Advances in Applied Mathematics, 2007 AbstractWe use elementary methods and operator identities to solve linear matrix differential equations and we obtain explicit formulas for the exponential of a matrix. We also give explicit constructions of solutions of scalar homogeneous equations with certain initial values, called dynamic solutions, that play an important role in the solution of ...
openaire +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Linear Parabolic Differential Equations of Arbitrary Order; General Boundary-Value Problems for Elliptic Equations [PDF]
, 1953 Felix E. Browder
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Theorems converse to Riemann’s on linear differential equations [PDF]
, 1906 D. R. Curtiss
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Analogue of Newton-Puiseux series for non-holonomic D-modules and factoring
, 2008 We introduce a concept of a fractional-derivatives series and prove that any linear partial differential equation in two independent variables has a fractional-derivatives series solution with coefficients from a differentially closed field of zero ...
Grigoriev, D.
core +1 more source