Results 131 to 140 of about 2,136,673 (353)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

A comparative study on residual power series method and differential transform method through the time-fractional telegraph equation

Nonlinear Engineering
In the present era of cutting-edge technologies powering electronic devices, energy systems, and modern telecommunication, a mathematical model called the telegraph equation plays a major role. It describes the wave propagation and diffusion processes in
Devshali Pratiksha, Singh Prince
doaj   +1 more source

Linear Operators and the General Solution of Elementary Linear Ordinary Differential Equations

, 2012
Norbert Euler
openalex   +2 more sources

Approximate Solution of the System of Linear Fractional Integro-Differential Equations of Volterra Using B- Spline Method [PDF]

, 2015
Adel A. Al-Marashi
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Stability of homogeneous nonstationary systems of differential-difference equations with linearly time delay

, 2019
Alexander V. Ekimov, Olga Chizhova, Uliana P. Zaranik   +2 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Solving linear Fredholm integro-differential equation by Nyström method

Journal of Applied Mathematics and Computational Mechanics, 2021
Boutheina Tair, Hamza Guebbai, Sami Segni, Mourad Ghiat   +3 more
doaj   +1 more source

On the Hyers–Ulam stability of the linear differential equation

, 2011
D. Popa, I. Raşa
semanticscholar   +1 more source