Results 141 to 150 of about 2,088,895 (372)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

The Dirac function in non-linear differential equations [PDF]

open access: bronze, 1958
Václav Doležal   +2 more
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Existence and uniqueness theorem of associated solutions of the stochastic differential system with measures

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2018
The Cauchy problem for stochastic differential system with measures is considered in the paper. Finite-difference with averaging system of stochastic differential equations with correspondence to Cauchy problem is investigated.
Artsiom Y. Rusetski
doaj  

A comparative study on residual power series method and differential transform method through the time-fractional telegraph equation

open access: yesNonlinear Engineering
In the present era of cutting-edge technologies powering electronic devices, energy systems, and modern telecommunication, a mathematical model called the telegraph equation plays a major role. It describes the wave propagation and diffusion processes in
Devshali Pratiksha, Singh Prince
doaj   +1 more source

On the solution of linear differential equations [PDF]

open access: yesAbstracts of the Papers Communicated to the Royal Society of London
The methods employed in this paper to effect the solution or reduction of linear differential equations consist of certain peculiar transformations, and each particular class of equations is transformed by a distinct process peculiarly its own.
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

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