Results 91 to 100 of about 5,342 (265)
Some procedures for solving special max-min fractional rank-two reverse-convex programming problems
Journal of Numerical Analysis and Approximation Theory, 2004 In this paper we suggest some procedures for solving two special classes of \(\max\)-\(\min\) fractional reverse-convex programs. We show that a special bilinear fractional max-min reverse-convex program can be solved by a linear reverse-convex ...
Doina Ionac, Ştefan Ţigan
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Analyses of the solution to a linear fractional functionals programming
Metrika, 1970 In this paper the effect of changing one constant of the Linear Fractional Functionals Programming problem has been discussed under the condition that the optimal basis for the original problem remains unaffected. In the changed form the optimal solution and new value of the objective functions are obtained.
openaire +2 more sources
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
صياغة وحل نماذج البرمجة الكسرية الخطية باستخدام طريقة لاكرانج المطورة
مجلة علوم ذي قار, 2019 In this paper Lagrange’s method was used to solve Fractional linear programming problems and then developed this method by using mathematical forms by which it can be possible to find the solution without using complex derivations.
رشيد بشير رحيمه
doaj
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
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Results in Control and OptimizationThis note presents a critical assessment of the paper authored by Sahoo et al. (2022) titled “Study on multi-objective linear fractional programming problem involving pentagonal intuitionistic fuzzy number” published in Results in Control and ...
Hassan Hassanpour, Javad Tayyebi
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source