Results 221 to 230 of about 8,884,990 (247)

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

Theoretical analysis of thermomechanical response for biological skin tissues. [PDF]

Sci Rep
Islam N, Das B, Lahiri A.
europepmc   +1 more source

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing

Advanced Science, EarlyView.
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Ke Liu, Xiyan Wang, Xiaozhen Liu, Chaoqi He, Da Qian, Xuli Meng, Liquan Zhu   +6 more
wiley   +1 more source

Adaptive SMC with direct dual inertial matrix compensation for spacecraft attitude-orbit dynamics. [PDF]

Sci Rep
Lu L, Xia L, Chai H, Li S, Liu Y.
europepmc   +1 more source

Robust SAR Waveform Design for Extended Target in Spectrally Dense Environments. [PDF]

Sensors (Basel)
Zhang R, Wu F, Gao B, Xu G, Wu J, Zhang J.   +5 more
europepmc   +1 more source

Solving the Portfolio Optimization Problem on a Photonic Quantum Computer. [PDF]

Entropy (Basel)
Grodzki Ł, Slysz M, Waligóra G.
europepmc   +1 more source

Joint Optimization of Trajectory-Resource Allocation and Deep Task Partial Offloading for MEC-Enabled Multi-UAV. [PDF]

Sensors (Basel)
Liu C, Wang Y, Mei H, Du S, Guo B.
europepmc   +1 more source

Explainable artificial intelligence-enabled intertwined logistics analytics with application in poultry vaccine distribution in the Northwest of Iran. [PDF]

Sci Rep
Mehravaran M, Nemati A.
europepmc   +1 more source

A first order method for linear programming parameterized by circuit imbalance. [PDF]

Math Program
Cole R, Hertrich C, Tao Y, Végh LA.
europepmc   +1 more source

The inverse optimal value problem for linear fractional programming

Operations Research Letters
We study the inverse optimal value problem for linear fractional programming, where the goal is to find the coefficients of the fractional objective function such that the resulting optimal objective function value is as close as possible to some given ...
Taewoo Lee, Oleg A. Prokopyev, Sina Nadi
exaly   +3 more sources