Results 111 to 120 of about 625,541 (288)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A NEW GENERATOR OF THIRD-DEGREE LINEAR FORMS

open access: yesПроблемы анализа
This paper examines linear forms of the third-degree, i.e., when the associated Stieltjes function satisfies a cubic equation with polynomial coefficients. A generator for third-degree forms is constructed. In fact, we study the stability of the third-
M. Khalfallah
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

A novel tubular transverse-flux moving-magnet linear oscillating generator designed for free-piston engines

open access: yesNext Energy
Linear generator is the most important component of free-piston engine generators, which are considered as ideal range extenders used in electric vehicles.
Zhaoping Xu, Qian Yao, Liang Liu
doaj   +1 more source

Assessment of disk MHD generators for a base load powerplant [PDF]

open access: yes
Results from a study of the disk MHD generator are presented. Both open and closed cycle disk systems were investigated. Costing of the open cycle disk components (nozzle, channel, diffuser, radiant boiler, magnet and power management) was done. However,
Chubb, D. L.   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

THE STUDY, DESIGN AND TESTING OF A LINEAR OSCILLATING GENERATOR WITH MOVING PERMANENT MAGNETS [PDF]

open access: yesCarpathian Journal of Electrical Engineering, 2015
This paper presents a study, design and testing of a Linear Oscillating Generator. There are presented the main steps of the magnetic and electric calculations for a permanent magnet linear alternator of fixed coil and moving magnets type. Finally it has
Teodora Susana OROS (POP)   +2 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Laboratory Tests of a Generator for a Linear MR Damper [PDF]

open access: yesTransactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2009
The paper is devoted to laboratory testing of an experimental electromagnetic generator supplying a linear magnetorheological (MR) damper. The structure of the generator is briefly outlined.
Bogdan SAPIŃSKI   +2 more
doaj  

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