Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl +6 more
wiley +1 more source
Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella +5 more
wiley +1 more source
Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source
Rank-Based Analysis of Linear Models Using R [PDF]
It is well-known that Wilcoxon procedures out perform least squares procedures when the data deviate from normality and/or contain outliers. These procedures can be generalized by introducing weights; yielding so-called weighted Wilcoxon (WW) techniques.
Jeff T. Terpstra, Joseph W. McKean
core
Exact optimal and adaptive inference in regression models under heteroskedasticity and non-normality of unknown forms [PDF]
In this paper, we derive simple point-optimal sign-based tests in the context of linear and nonlinear regression models with fixed regressors. These tests are exact, distribution-free, robust against heteroskedasticity of unknown form, and they may be ...
Taamouti, Abderrahim, Dufour, Jean-Marie
core +1 more source
Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph +5 more
wiley +1 more source
The limiting power of autocorrelation tests in regression models with linear restrictions
It is well known that the Durbin-Watson and several other tests for first-order autocorrelation have limiting power of either zero or one in a linear regression model without an intercept, and tend to a constant lying strictly between these values when ...
Wan, Alan, Zou, Guohua, Banerjee, Anurag
core +1 more source
Applying neuro-fuzzy modeling to evaluate and enhance badminton footwork training
Purpose To design a coach-interpretable movement quality score for badminton footwork training using an adaptive neuro-fuzzy inference system. Methodology We derived compact biomechanical descriptors of timing, kinematics, dynamics, and stability from ...
Jiayun Xu
doaj +1 more source
Applying fuzzy logic to estimate the parameters of the length-weight relationship
We evaluated three mathematical procedures to estimate the parameters of the relationship between weight and length for Cichla monoculus: least squares ordinary regression on log-transformed data, non-linear estimation using raw data and a mix of ...
S. D. Bitar +2 more
doaj +1 more source
Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu +4 more
wiley +1 more source

