Results 211 to 220 of about 82,622 (268)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Light-Driven Reconfigurable Logic in a Monolithic Perovskite Device via Nonlinear Photoresponse Switching. [PDF]

Adv Mater
Ahn D, Jang Y, Lee M, Jeon W, Yoon Y, Lee H, Sasikala AA, Lim N, Balamurugan C, Kim H, Jung GY, Kwon S, Seo M, Pak Y.   +13 more
europepmc   +1 more source

An Integrated NLP‐ML Framework for Property Prediction and Design of Steels

Advanced Science, EarlyView.
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju, Adithya Umanath Rai, Jose Thomson, Marzie Ghorbani, Shujing Zhao, Nick Birbilis   +5 more
wiley   +1 more source

Conceptualization and implementation of community social prescribing evaluation: a case study of the co-designed <i>Connect Local</i> and <i>Spark</i> programs. [PDF]

Front Public Health
Ogrin R, Corsini N, Scott J, Jarvis A, Robinson E, Bonell S, Lowthian JA.   +6 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Overcoming quadratic hardware scaling for a fully connected digital oscillatory neural network. [PDF]

Front Neurosci
Haverkort BF, Todri-Sanial A.
europepmc   +1 more source

Beyond temperature: Why climate adaptation in agriculture needs a systems approach. [PDF]

Proc Natl Acad Sci U S A
Basso B.
europepmc   +1 more source

On Quantum Relations. [PDF]

Entropy (Basel)
Dubois F, Toffano Z.
europepmc   +1 more source

Coupled polarization dynamics and charge tunneling enable reconfigurable heterojunctions. [PDF]

Nat Commun
Li C, Yu T, Zhang Z, Deng Q, Hui F, Wang Z, Lanza M, Sun L.   +7 more
europepmc   +1 more source