Results 131 to 140 of about 1,146,405 (217)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

CBCT Validation Study on Intraclass Correlation for Linear Measurements in Peri-implantitis: an Observational Study. [PDF]

J Oral Maxillofac Res
Rodriguez AB, Ayyildiz BG, Ayyildiz H, Narvekar A, Elnagar MH, Schmerman M, Viana G, Nares S, Tözüm TF.   +8 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Body size prediction in scorpions: a phylogenetic comparative examination of linear measurements of individual body parts. [PDF]

PeerJ
Foerster SÍA.
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Comparison of volumetric and linear measurements of intestinal inflammation and treatment response in children with newly diagnosed ileal Crohn disease. [PDF]

Eur Radiol
Derinkuyu BE, Bard A, Naim I, Tkach JA, Denson LA, Dillman JR.   +5 more
europepmc   +1 more source

Are Linear Measurements of the Nucleus Basalis of Meynert Suitable as a Diagnostic Biomarker in Mild Cognitive Impairment and Alzheimer Disease? [PDF]

AJNR Am J Neuroradiol, 2019
Jethwa KD, Dhillon P, Meng D, Auer DP, Alzheimer’s Disease Neuroimaging Initiative.   +4 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Evaluation of the agreement of horizontal and vertical linear measurements obtained from digital models, printed models and direct measurements. [PDF]

Dental Press J Orthod
Mota-Júnior SL, Abreu ACT, Santos BVMD, Marangon ALL, Campos MJDS, Vitral RWF.   +5 more
europepmc   +1 more source

Near-optimal matrix recovery from random linear measurements. [PDF]

Proc Natl Acad Sci U S A, 2018
Romanov E, Gavish M.
europepmc   +1 more source