Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
grafify online: A web app for graphing and statistical analysis. [PDF]
Shenoy AR.
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Short-term effects of different toothpaste formulations on total salivary calcium: A randomized crossover study. [PDF]
Aminy L +4 more
europepmc +1 more source
Effects of Indirect Pupillary Light Reflex Stimulation With Colored Light on Corneal Specular Microscopy Performance in Dogs. [PDF]
Kim M, Suk H, Kang S, Seo K.
europepmc +1 more source
Serial Changes in Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Implantation: Associations With Ischemic Heart Disease and Left Ventricular End-Diastolic Diameter. [PDF]
Tanaka K +24 more
europepmc +1 more source
Shared Decision-Making and Patient Enablement in Outpatient Rehabilitation: An Observational Study. [PDF]
Iwasawa N +4 more
europepmc +1 more source
Hand Dominance Influences Motor Recovery Trajectories Following Stroke: A Longitudinal Study. [PDF]
Gutterman J +10 more
europepmc +1 more source
Exercise adherence and wrist function recovery after distal radius fracture surgery in older adults: a 12 week prospective longitudinal study. [PDF]
Ji S, Sun Y, Zhu Y.
europepmc +1 more source
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Statistical Methods in Medical Research, 2022The generalized linear mixed model (GLMM) is one of the most common method in the analysis of longitudinal and clustered data in biological sciences. However, issues of model complexity and misspecification can occur when applying the GLMM. To address these issues, we extend the standard GLMM to a nonlinear mixed-effects model based on quasi-linear ...
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