Results 181 to 190 of about 24,949,533 (304)

Multiple imputation methods for handling incomplete longitudinal and clustered data where the target analysis is a linear mixed effects model. [PDF]

Biom J, 2020
Huque MH, Moreno-Betancur M, Quartagno M, Simpson JA, Carlin JB, Lee KJ.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Impact of Sociodemographic Factors on Job Insecurity Among Obstetric Nurses Under the Low Fertility Background: A Linear Mixed-Effects Model Analysis and Targeted Intervention Strategies. [PDF]

J Multidiscip Healthc
Chen D, Ma J.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

OLS Estimator for a Mixed Regressive, Spatial Autoregressive Model: Extended Version [PDF]

We find the asymptotic distribution of the OLS estimator of the parameters $% \beta$ and $\rho$ in the mixed spatial model with exogenous regressors $% Y_n=X_n\beta+\rho W_nY_n+V_n$.
Mynbaev, Kairat
core  

The Impact of Anosmia on Intimacy: A Linear Mixed-Effects Model Analysis of Sexual Wellbeing Following COVID-19. [PDF]

Int J Environ Res Public Health
Miclet A, Mollaioli D, Lauriola M, Ciocca G, Sansone A, Jannini EA, Limoncin E.   +6 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Preoperative Functional Disability and Perioperative Life-space Mobility in Older Patients with Lumbar Spinal Stenosis: A Generalized Linear Mixed-effects Model Analysis. [PDF]

Phys Ther Res
Ishizuka D, Nozaki S, Minezaki H, Ota T, Asakawa Y.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Obsessive Beliefs, Metacognitive Beliefs, and Rumination in Parents of Adolescents with and Without Obsessive-Compulsive Disorder: A Linear Mixed-Effects Model. [PDF]

Brain Sci
Mısır E, Özbek MM.
europepmc   +1 more source