Results 211 to 220 of about 2,452,838 (337)

miRglmm: a generalized linear mixed model of isomiR-level counts improves estimation of miRNA-level differential expression and uncovers variable differential expression between isomiRs. [PDF]

Genome Biol
Baran AM, Patil AH, Aparicio-Puerta E, Jun SH, Halushka MK, McCall MN.   +5 more
europepmc   +1 more source

Detecting differentially expressed circular RNAs from multiple quantification methods using a generalized linear mixed model. [PDF]

Comput Struct Biotechnol J, 2022
Buratin A, Romualdi C, Bortoluzzi S, Gaffo E.   +3 more
europepmc   +1 more source

Advancing the Science of Spatial Neglect Rehabilitation: An Improved Statistical Approach with Mixed Linear Modeling [PDF]

, 2013
Kelly M. Goedert, Raymond C. Boston, Anna M. Barrett   +2 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

An expression-directed linear mixed model discovering low-effect genetic variants. [PDF]

Genetics
Li Q, Bian J, Qian Y, Kossinna P, Gau C, Gordon PMK, Zhou X, Guo X, Yan J, Wu J, Long Q.   +10 more
europepmc   +1 more source

Linear mixed model analysis to evaluate correlations between remdesivir adverse effects with age and gender of patients with mild Covid-19 pneumonia. [PDF]

J Med Virol, 2022
Sedighi M, Amanollahi A, Moradi Moghaddam O, Basir Ghafouri H, Hoseini SE, Tavakoli N.   +5 more
europepmc   +1 more source

Anxiety and depression sub-scale scores from the 10-item Kessler Psychological Distress Scale for Ontario education workers participating in the COVID-19 Cohort Study, February 18, 2021 to December 22, 2023, estimates using linear mixed effects models.

Iris Gutmanis (19454389), Brenda L. Coleman (20694988), Kelly Ramsay (21356061), Robert Maunder (12090868), Susan J. Bondy (3723163), Kailey Fischer (22075181), Veronica Zhu (22075184), Allison McGeer (196862)   +7 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The effect of 12-week long exercise intervention, and 2-weeks of detraining period on lower limbs strength parameters and postural stability in older adults: a linear mixed model analysis. [PDF]

BMC Geriatr
Svobodová L, Sebera M, Vodička T, Svobodová A, Horáková A, Stračárová N, Svobodová Š, Eclerová V, Vespalec T, Kasović M, Paludo AC, Bienertova-Vasku J, Gimunová M.   +12 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source