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BLMM: Parallelised computing for big linear mixed models [PDF]

open access: yesNeuroImage, 2022
Within neuroimaging large-scale, shared datasets are becoming increasingly commonplace, challenging existing tools both in terms of overall scale and complexity of the study designs.
Thomas Maullin-Sapey, Thomas E. Nichols
doaj   +2 more sources

Subset selection for linear mixed models. [PDF]

open access: yesBiometrics, 2023
AbstractLinear mixed models (LMMs) are instrumental for regression analysis with structured dependence, such as grouped, clustered, or multilevel data. However, selection among the covariates—while accounting for this structured dependence—remains a challenge. We introduce a Bayesian decision analysis for subset selection with LMMs. Using a Mahalanobis
Kowal DR.
europepmc   +4 more sources

Model Selection in Linear Mixed Models

open access: yesStatistical Science, 2013
Linear mixed effects models are highly flexible in handling a broad range of data types and are therefore widely used in applications. A key part in the analysis of data is model selection, which often aims to choose a parsimonious model with other ...
Müller, Samuel   +2 more
core   +4 more sources

Sparse Probit Linear Mixed Model [PDF]

open access: yesMachine Learning, 2017
Linear Mixed Models (LMMs) are important tools in statistical genetics. When used for feature selection, they allow to find a sparse set of genetic traits that best predict a continuous phenotype of interest, while simultaneously correcting for various ...
Cunningham, John P.   +5 more
core   +2 more sources

Federated generalized linear mixed models for collaborative genome-wide association studies [PDF]

open access: yesiScience, 2023
Summary: Federated association testing is a powerful approach to conduct large-scale association studies where sites share intermediate statistics through a central server. There are, however, several standing challenges.
Wentao Li   +3 more
doaj   +2 more sources

"Prediction in Multivariate Mixed Linear Models" [PDF]

open access: yesJOURNAL OF THE JAPAN STATISTICAL SOCIETY, 2003
The multivariate mixed linear model or multivariate components of variance model with equal replications is considered.The paper addresses the problem of predicting the sum of the regression mean and the random e ects.When the feasible best linear ...
M. S. Srivastava, Tatsuka Kubokawa
core   +4 more sources

Neighborhood-level heterogeneity in childhood morbidity through generalized linear mixed models [PDF]

open access: yesFrontiers in Public Health
ObjectiveChildhood morbidities are crucial for improving long-term public health outcomes. This study aimed to examine the existence of child-specific and regional variation in childhood morbidity based on the cross-cutting study of the Performance ...
Endeshaw A. Derso   +8 more
doaj   +2 more sources

Network analysis of longitudinal electronic health records using linear mixed models [PDF]

open access: yesBioData Mining
Background The accelerating development of healthcare data stored in electronic health records (EHRs) has created novel opportunities for biomedical research.
Marina Vargas-Fernández   +3 more
doaj   +2 more sources

Linear Mixed Models [PDF]

open access: yes, 2022
AbstractThe linear mixed model framework is explained in detail in this chapter. We explore three methods of parameter estimation (maximum likelihood, EM algorithm, and REML) and illustrate how genomic-enabled predictions are performed under this framework.
Osval Antonio Montesinos López   +2 more
  +4 more sources

partR2: partitioning R2 in generalized linear mixed models [PDF]

open access: yesPeerJ, 2021
The coefficient of determination R2 quantifies the amount of variance explained by regression coefficients in a linear model. It can be seen as the fixed-effects complement to the repeatability R (intra-class correlation) for the variance explained by ...
Martin A. Stoffel   +2 more
doaj   +2 more sources

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