Results 11 to 20 of about 1,982,495 (283)

Variational Bayesian Inference in High-Dimensional Linear Mixed Models

open access: yesMathematics, 2022
In high-dimensional regression models, the Bayesian lasso with the Gaussian spike and slab priors is widely adopted to select variables and estimate unknown parameters. However, it involves large matrix computations in a standard Gibbs sampler.
Jieyi Yi, Niansheng Tang
doaj   +1 more source

Polygenic modeling with bayesian sparse linear mixed models. [PDF]

open access: yesPLoS Genetics, 2013
Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies.
Xiang Zhou   +2 more
doaj   +1 more source

Gradient boosting for linear mixed models [PDF]

open access: yesThe International Journal of Biostatistics, 2021
Abstract Gradient boosting from the field of statistical learning is widely known as a powerful framework for estimation and selection of predictor effects in various regression models by adapting concepts from classification theory. Current boosting approaches also offer methods accounting for random effects and thus enable prediction ...
Griesbach, Colin   +2 more
openaire   +5 more sources

CytoGLMM: conditional differential analysis for flow and mass cytometry experiments

open access: yesBMC Bioinformatics, 2021
Background Flow and mass cytometry are important modern immunology tools for measuring expression levels of multiple proteins on single cells. The goal is to better understand the mechanisms of responses on a single cell basis by studying differential ...
Christof Seiler   +7 more
doaj   +1 more source

Multiple testing correction in linear mixed models. [PDF]

open access: yes, 2016
BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar   +3 more
core   +2 more sources

Bayesian Inference for Spatial Beta Generalized Linear Mixed Models [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2018
In some applications, the response variable assumes values in the unit interval. The standard linear regression model is not appropriate for modelling this type of data because the normality assumption is not met. Alternatively, the beta regression model
L. Kalhori Nadrabadi, M. Mohhamadzadeh
doaj   +1 more source

Bayesian Linear Mixed Models with Polygenic Effects

open access: yesJournal of Statistical Software, 2018
We considered Bayesian estimation of polygenic effects, in particular heritability in relation to a class of linear mixed models implemented in R (R Core Team 2018).
Jing Hua Zhao   +2 more
doaj   +1 more source

Generalized linear mixed models can detect unimodal species-environment relationships [PDF]

open access: yesPeerJ, 2013
Niche theory predicts that species occurrence and abundance show non-linear, unimodal relationships with respect to environmental gradients. Unimodal models, such as the Gaussian (logistic) model, are however more difficult to fit to data than linear ...
Tahira Jamil, Cajo J.F. ter Braak
doaj   +2 more sources

Fitting Linear Mixed-Effects Models Using lme4

open access: yesJournal of Statistical Software, 2015
Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model is described in
Douglas Bates   +3 more
doaj   +1 more source

Generalized fiducial inference for normal linear mixed models [PDF]

open access: yes, 2012
While linear mixed modeling methods are foundational concepts introduced in any statistical education, adequate general methods for interval estimation involving models with more than a few variance components are lacking, especially in the unbalanced ...
Cisewski, Jessi, Hannig, Jan
core   +4 more sources

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