Results 161 to 170 of about 7,333,462 (342)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Non-linear model predictive control for variable speed hydropower. [PDF]
Nepal T +5 more
europepmc +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Broad Applications of Distributed Lag Non-Linear Model in Public Health: A Comprehensive Review. [PDF]
Shafqat A, Park E.
europepmc +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
LGBTQ + Affirmative CBT: a hierarchical linear model of longitudinal outcomes and mechanisms of change. [PDF]
Craig SL +9 more
europepmc +1 more source
Indexing and partitioning the spatial linear model for large data sets. [PDF]
Ver Hoef JM +4 more
europepmc +1 more source

