Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Addressing multicollinearity in general linear model: A novel approach for ridge parameter with performance comparison. [PDF]
PLoS OneLuqman M, Bhatti SH, Aydin D, Jamil M.
europepmc +1 more source
Indexing and partitioning the spatial linear model for large data sets. [PDF]
PLoS One, 2023 Ver Hoef JM +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Diagnosis of Cushing's syndrome with generalized linear model and development of mobile application. [PDF]
Medicine (Baltimore)Aydemir M, Çakir M, Oral O, Yilmaz M.
europepmc +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Lagged effects of risk factors on the disability of older adults: A distributed lag non-linear model approach. [PDF]
Int J Nurs SciMao Y, Guo Z, Gao W, Zhang Y, Jin J.
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Teacher-focused approach to foster student engagement - a hierarchical linear model based on Chinese college students' psychological capital. [PDF]
BMC PsycholHao XY, He Y, Zhang DX, Li XY.
europepmc +1 more source
Integrated partially linear model for multi-center studies with heterogeneity and batch effect in covariates. [PDF]
Statistics (Ber), 2023 Yang L, Shao Y.
europepmc +1 more source