Results 171 to 180 of about 1,606,033 (248)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Reassessing the validity of using weighted linear models to implement multi-generational GWAS-by-subtraction: a response to Evans et al. [PDF]

BMC Res Notes
Woolf B, Gill D, Munafò M, Burgess S.
europepmc   +1 more source

Error analysis and modeling of the racetrack magnetohydrodynamic linear motion sensor [PDF]

Mengjie Xu, Jiahui Mo, Chenyan Xia, Lei Yang, Feng Ji, Jingjing Chen, Xingfei Li   +6 more
openalex   +1 more source

B.R.S. renormalisation of some on-shell closed algebras of symmetry transformations : N=2 and 4 supersymmetric non-linear sigma models [PDF]

, 1994
Guy Bonneau
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

COLA-GLM: collaborative one-shot and lossless algorithms of generalized linear models for decentralized observational healthcare data. [PDF]

NPJ Digit Med
Wu Q, Reps JM, Li L, Zhang B, Lu Y, Tong J, Zhang D, Lumley T, Brand MT, Van Zandt M, Falconer T, He X, Huang Y, Li H, Yan C, Tang G, Williams AE, Wang F, Bian J, Malin B, Hripcsak G, Schuemie MJ, Lu Y, Drew S, Zhou J, Asch DA, Chen Y.   +26 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

A new <i>p</i>-value based multiple testing procedure for generalized linear models. [PDF]

Stat Comput
Rilling J, Tang CY.
europepmc   +1 more source

A new Bartlett-based homogeneity test for linear regression models

Yasser Al Zaim, Abdulrahman AlAita
openalex   +2 more sources

Proposal of the linear models of crops production functions in the Czech Republic [PDF]

, 2012
Václav Voltr, Jan Leština, Pavel Froněk, Soňa Partynglová   +3 more
openalex   +1 more source