Results 61 to 70 of about 283,344 (265)

Improved study on position measurement system for linear motor applied in electromagnetic launch system

open access: yesCES Transactions on Electrical Machines and Systems, 2019
The linear motor applied in electromagnetic emission system uses a closed loop position control strategy, which needs a set of position measurement system with high reliability, high resolution and integration to achieve real-time acquisition and ...
Wanzhi Rui   +3 more
doaj   +1 more source

Coupled Circuit and Magnetic Model for a Transverse Flux Permanent Magnet Linear Motor

open access: yesIEEE Access, 2020
In this paper, a strong coupling between magnetic and electric phenomena is provided allowing to have an accurate and high-speed coupled model. A coupled circuit and magnetic model for an E-core transverse flux permanent magnet linear motor (TFPMLM) is ...
Dongshan Fu   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Thrust Ripple Reduction of Permanent Magnet Linear Synchronous Motor Based on Improved Pole Shape for Electromagnetic Launcher System

open access: yesIranian Journal of Electrical and Electronic Engineering, 2019
In this paper, a new design of permanent magnet linear synchronous motor (PMLSM) for electromagnetic launcher system (EMLs) has been investigated in terms of the requisite amount of average launching thrust force and thrust force ripple minimization ...
H. Sheykhvazayefi   +2 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Study of the Injection Control Strategies of a Compression Ignition Free Piston Engine Linear Generator in a One-Stroke Starting Process

open access: yesEnergies, 2016
For a compression ignition (CI) free piston engine linear generator (FPLG), injection timing is one of the most important parameters that affect its performance, especially for the one-stroke starting operation mode.
Huihua Feng   +4 more
doaj   +1 more source

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