Results 91 to 100 of about 407,668 (252)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Linear-Complexity Overhead-Optimized Random Linear Network Codes
Sparse random linear network coding (SRLNC) is an attractive technique proposed in the literature to reduce the decoding complexity of random linear network coding. Recognizing the fact that the existing SRLNC schemes are not efficient in terms of the required reception overhead, we consider the problem of designing overhead-optimized SRLNC schemes. To
Mahdaviani, Kaveh +2 more
openaire +2 more sources
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
PACE: Redundancy Engineering in RLNC for Low-Latency Communication
Random linear network coding (RLNC) is attractive for data transfer as well as data storage and retrieval in complex and unreliable settings. The existing systematic RLNC approach first sends all source symbols in a generation without encoding followed ...
Sreekrishna Pandi +5 more
doaj +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
On the Packet Decoding Delay of Linear Network Coded Wireless Broadcast [PDF]
Mingchao Yu +2 more
openalex +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Instantly Decodable versus Random Linear Network Coding: A Comparative Framework for Throughput and Decoding Delay Performance [PDF]
Parastoo Sadeghi, Mingchao Yu
openalex +1 more source

