Results 101 to 110 of about 5,164,048 (315)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
On A Certain Subclass Of Analytic Functions Defined By Linear Operator [PDF]
, 2021 B. Venkateswarlu +3 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Pseudospectra of the direct sum of linear operators in ultrametric Banach spaces
Қарағанды университетінің хабаршысы. Математика сериясыIn this paper, a characterization of essential pseudospectra of bounded linear operators on ultrametric Banach spaces over a spherically complete field was given and the notions of pseudospectra and condition pseudospectra of the direct sum of linear ...
J. Ettayb
doaj +1 more source
Extracting Koopman Operators for Prediction and Control of Non-linear Dynamics Using Two-stage Learning and Oblique Projections [PDF]
, 2023 Daisuke Uchida, Karthik Duraisamy
openalex +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Local saturation of a positive linear convolution operator [PDF]
, 2014 Hee Sun Jung, Ryozi Sakai
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Weighted A-statistical convergence for sequences of positive linear operators. [PDF]
ScientificWorldJournal, 2014 Mohiuddine SA, Alotaibi A, Hazarika B.
europepmc +1 more source