Results 41 to 50 of about 5,164,048 (315)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
On a Linear Differential Game of Pursuit with Integral Constraints in ℓ2
MathematicsIn this paper, we study the stability, controllability, and differential game of pursuit for an infinite system of linear ODEs in ℓ2. The system we consider has a special right-hand side, which is not diagonal and serves as a toy model for controllable ...
Ibroximjon Zaynabiddinov +3 more
doaj +1 more source
Correction and Addendum to: “On the Generalized Drazin–Riesz Inverse for Closed Linear Operators” [PDF]
, 2023 Othman Abad, Hassane Zguitti
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The degree of nondensifiability of linear bounded operators and its applications
Applied General TopologyIn the present paper we define the degree of nondensifiability (DND for short) of a bounded linear operator T on a Banach space and analyze its properties and relations with the Hausdorff measure of non-compactness (MNC for short) of T. As an application
Gonzalo García, Gaspar Mora
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On the extension of linear operators
International Journal of Mathematics and Mathematical Sciences, 2001 It is well known that the Hahn-Banach theorem, that is, the extension theorem for bounded linear functionals, is not true in general for bounded linear operators. A characterization of spaces for which it is true was published by Kakutani in 1940.
John J. Saccoman
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The Approximation of a Modified Baskakov Operator
Journal of Mathematics, 2023 Because of their simple form and high quality, linear arithmetical operators, particularly linear positive operators, are very popular. The number of in-depth studies on linear operator approximation is extensive, and the majority of the published ...
Ma Yingdian, Wang Weimeng
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source