Results 91 to 100 of about 23,073 (264)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Exact solutions of the (1+1)-dissipative Westervelt equation using an optimal system of Lie sub-algebras and modified simple equation method

Partial Differential Equations in Applied Mathematics
The Westervelt model is a non-linear partial differential equation that models sound propagation and its effects in non-linear media. In this paper, we obtain exact invariant solutions of the (1+1)-dimensional dissipative Westervelt equation using Lie ...
Theko M. Sekhesa, Ngaka J. Nchejane, Wetsi D. Poka, Kalebe M. Kalebe   +3 more
doaj   +1 more source

Ordinary differential equations in linear topological space, II

Journal of Differential Equations, 1969
Ordinary differential equations in linear topological space extended from Fattorini investigation, emphasizing use of linear ...
openaire   +4 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

On Geometric-Analytic Aspects of Solvable Nonlinear Ordinary Differential Equations and Some Applications

Mathematics
A geometric-analytic approach to studying invariants of solvable nonlinear ordinary differential equations is developed. In particular, there is described in detail a general scheme of constructing solvable nonlinear ordinary differential equations ...
Anatolij K. Prykarpatski, Victor A. Bovdi, Petro Y. Pukach, Yarema A. Prykarpatsky, Myroslava I. Vovk   +4 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

A comparative study on residual power series method and differential transform method through the time-fractional telegraph equation

Nonlinear Engineering
In the present era of cutting-edge technologies powering electronic devices, energy systems, and modern telecommunication, a mathematical model called the telegraph equation plays a major role. It describes the wave propagation and diffusion processes in
Devshali Pratiksha, Singh Prince
doaj   +1 more source

A Class of Collocation Hybrid Backward Differentiation Method for Initial Value Problems of Ordinary Differential Equations

Fountain Journal of Natural and Applied Sciences (FUJNAS)
The development of a linear multistep method for initial value problems of Ordinary Differential Equations (O.D.E.s) has been the subject of investigation for some time. In this work, a class of hybrid backward differentiation methods with step number k=
Adewole Ajileye, Ojo Olamiposi Aduroja
doaj   +1 more source