Results 51 to 60 of about 93,018 (292)

Acceleration of a trailing positron bunch in a plasma wakefield accelerator

Scientific Reports, 2017
High gradients of energy gain and high energy efficiency are necessary parameters for compact, cost-efficient and high-energy particle colliders. Plasma Wakefield Accelerators (PWFA) offer both, making them attractive candidates for next-generation ...
A. Doche, C. Beekman, S. Corde, J. M. Allen, C. I. Clarke, J. Frederico, S. J. Gessner, S. Z. Green, M. J. Hogan, B. O’Shea, V. Yakimenko, W. An, C. E. Clayton, C. Joshi, K. A. Marsh, W. B. Mori, N. Vafaei-Najafabadi, M. D. Litos, E. Adli, C. A. Lindstrøm, W. Lu   +20 more
doaj   +1 more source

Emittance growth in linear induction accelerators

, 2014
The Dual-Axis Radiographic Hydrotest (DARHT) facility uses bremsstrahlung radiation source spots produced by the focused electron beams from two linear induction accelerators (LIAs) to radiograph large hydrodynamic experiments driven by high explosives ...
Carlson, C. A., Ekdahl, C. A., Frayer, D. K., McCuistian, B. T., Mostrum, C., Schulze, M. E., Thoma, C. H.   +6 more
core   +1 more source

High throughput data streaming of individual longitudinal electron bunch profiles in a storage ring with single-shot electro-optical sampling [PDF]

, 2018
The development of fast detection methods for comprehensive monitoring of electron bunches is a prerequisite to gain comprehensive control over the synchrontron emission in storage rings with their MHz repetition rate.
Blomley, Edmund, Bründermann, Erik, Caselle, Michele, Funkner, Stefan, Hiller, Nicole, Müller, Anke-Susanne, Nasse, Michael J., Niehues, Gudrun, Rota, Lorenzo, Schönfeldt, Patrik, Walther, Sophie, Weber, Marc   +11 more
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Sub-per-mille bunch energy spread in a quasi-linear laser-wakefield accelerator via periodical de-chirpings

Communications Physics
Plasma-wakefield-based acceleration technology has enabled the generation of very bright particle bunches of ultrashort duration, micrometer size and low emittance.
Changhai Yu, Zhiyong Qin, Zhongtao Xiang, Ya Huang, Jiansheng Liu   +4 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Beam-based identification of magnetic field errors in a synchrotron using deep Lie map networks

Physical Review Accelerators and Beams
We report on the recovery of both linear and nonlinear optics in a hadron synchrotron using the novel deep Lie map network (DLMN) approach. The DLMN enables the construction of a detailed accelerator model by integrating charged particle dynamics with ...
Conrad Caliari, Adrian Oeftiger, Oliver Boine-Frankenheim   +2 more
doaj   +1 more source

A descrição do funcionamento de um motor Homopolar linear e suas aplicações: Ilustrando o funcionamento de um acelerador de partículas

Revista Brasileira de Ensino de Física
Neste trabalho exploramos o potencial didático de um motor homopolar linear com o objetivo de ilustrar o princípio de funcionamento de um acelerador de partículas.
Adriano Doff, Romeu M. Szmoski
doaj   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Efficient positron trapping and extraction with a center-hole SiC remoderator

New Journal of Physics, 2022
Trapping technologies of positrons, the antimatter counterpart of electrons, are indispensable for various atomic, molecular, and optical experiments and for material analyses that use positron swarms.
Koji Michishio, Hiroyuki Higaki, Akira Ishida, Nagayasu Oshima   +3 more
doaj   +1 more source