Results 81 to 90 of about 27,263 (307)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Optimal Design of Permanent Magnet Linear Generator and Its Application in a Wave Energy Conversion System

open access: yesEnergies, 2018
The emerging global wave energy industry has great potential to contribute to the world’s energy needs. However, one of the key challenges in designing a wave energy converter (WEC) is the wave energy generator.
Hong-wei Fang   +2 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Improved Linear Active Disturbance Rejection Controller Control Considering Bus Voltage Filtering in Permanent Magnet Synchronous Generator

open access: yesIEEE Access, 2020
In the permanent magnet direct drive wind power generation system, the direct current (DC) bus voltage signal of the converter is usually used as the feedback of the voltage outer loop.
Xuesong Zhou   +3 more
doaj   +1 more source

Investigations on the performances of the electrical generator of a rim-driven marine current turbine” [PDF]

open access: yes, 2014
In this paper, the electrical generator of a rim-driven horizontal-axis current turbine is modeled in detail. Its main characteristics and performances are evaluated (efficiency, mass, cost, etc).
CHARPENTIER, Jean-Frederic   +3 more
core   +1 more source

A low-speed linear harmonic generator for grid-tied and stand-alone operation using hybrid excitation topology [PDF]

open access: yes, 2015
Paper no. BP-09Since intermediate mechanical conversion mechanisms for speed, torque and motion conversion can be entirely eliminated, the direct-drive wave power generation attracts more and more attention [1].
Chau, KT, Ching, TW, Li, WL, Liu, C
core   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

Design and analysis of tubular permanent magnet linear generator for small-scale wave energy converter

open access: yesAIP Advances, 2017
This paper reports the design and analysis of a tubular permanent magnet linear generator (TPMLG) for a small-scale wave-energy converter. The analytical field computation is performed by applying a magnetic vector potential and a 2-D analytical model to
Jeong-Man Kim   +5 more
doaj   +1 more source

Overview of NASA Magnet and Linear Alternator Research Efforts [PDF]

open access: yes
The Department of Energy, Lockheed Martin, Stirling Technology Company, and NASA Glenn Research Center are developing a high-efficiency, 110 watt Stirling Radioisotope Generator (SRG110) for NASA Space Science missions.
Geng, Steven M.   +2 more
core   +1 more source

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