Results 141 to 150 of about 3,136,120 (312)
Comparison of several non-linear-regression methods for fitting the Michaelis-Menten equation [PDF]
Luděk Matyska, Jan Kovář
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Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source
The non-linearity of parent-offspring regression
Akira Nishida+4 more
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Earthing effects on mitochondrial function: ATP production and ROS generation
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
Linear and logistic regression: A medical perspective [PDF]
Logistic regression as the standard tool for extending the concepts of linear regression to binary outcomes. Binary outcomes have two states, such as death (dead or alive) or allergic reaction (present or absent), in contrast to continuous variables ...
S. Gothai Nachiyar+2 more
doaj
Non‐linear phylogenetic regression using regularised kernels
Phylogenetic regression is a type of generalised least squares (GLS) method that incorporates a modelled covariance matrix based on the evolutionary relationships between species (i.e. phylogenetic relationships).
Ulises Rosas‐Puchuri+4 more
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A Strategy for Efficient Sample Selection in Simple Linear Regression Problems with Unequal per unit Sampling Costs [PDF]
Peter Marshall, J. P. Demaerschalk
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Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni+4 more
wiley +1 more source
A note on numerical solutions of multiple linear regression
Hirohiko Nisimura
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