Results 161 to 170 of about 843,130 (317)

Linear stability of charged warm holes

open access: yesEuropean Physical Journal C: Particles and Fields
Charged black holes are known to suffer from an interior instability associated with the presence of the Cauchy horizon. Recently, a hairy charged black hole was proposed that avoids the formation of a Cauchy horizon.
Radouane Gannouji   +1 more
doaj   +1 more source

Integrability and Linear Stability of Nonlinear Waves. [PDF]

open access: yesJ Nonlinear Sci, 2018
Degasperis A, Lombardo S, Sommacal M.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The linear stability of Hunt-Rayleigh-Bénard flow. [PDF]

open access: yesPhys Fluids (1994), 2017
Qi TY, Liu C, Ni MJ, Yang JC.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

STability of linear stochastic systems

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2012
In this paper the problem of modeling the movement of the linear system under the influence of determined and stochastic parametric load had been studied by the example of cable-stayed girder.
I V Nabatov
doaj  

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