Sensor Selection and State Estimation for Unobservable and Non-Linear System Models. [PDF]
Sensors (Basel), 2021 Devos T +4 more
europepmc +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Decentralized stabilization of fractional positive descriptor continuous-time linear systems
International Journal of Applied Mathematics and Computer Science, 2018 A method for decentralized stabilization of fractional positive descriptor linear systems is proposed. Necessary and sufficient conditions for decentralized stabilization of fractional positive descriptor linear systems are established. The efficiency of
Kaczorek Tadeusz
doaj +1 more source
The Liouville Formula for the Uncertain Homogeneous Linear System and Explicit Solutions of the System. [PDF]
Differ Equ Dyn Syst, 2021 Roomi V, Ahmadi HR.
europepmc +1 more source
Structural Completeness of a Multi-channel Linear System with Dependent Parameters
, 2020 It is well known that the "fixed spectrum" {i.e., the set of fixed modes} of a multi-channel linear system plays a central role in the stabilization of such a system with decentralized control.
Liu, Fengjiao, Morse, A. Stephen
core
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Non-linear System of Multi-order Fractional Differential Equations: Theoretical Analysis and a Robust Fractional Galerkin Implementation. [PDF]
J Sci Comput, 2022 Faghih A, Mokhtary P.
europepmc +1 more source
Linear Invariants for Linear Systems
, 2021 A central question in verification is characterizing when a system has invariants of a certain form, and then synthesizing them. We say a system has a $k$ linear invariant, $k$-LI in short, if it has a conjunction of $k$ linear (non-strict) inequalities -- equivalently, an intersection of $k$ (closed) half spaces -- as an invariant.
openaire +2 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
A boundary value problem for a system of ordinary linear differential equations of the first order [PDF]
, 1926 Gilbert Ames Bliss
openalex +1 more source