Results 81 to 90 of about 2,659,919 (342)

Scalable Control Design for K-positive Linear Systems [PDF]

open access: yesarXiv, 2020
Systems whose variable are constrained to be positive allow computationally efficient control design. We generalize these results to linear systems which leave a cone invariant. This is a wider class of systems than positive systems. We revisit classical results on stability and dissipativity of positive linear systems and show how scalable conditions ...
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Classifications of Linear Controlled Systems [PDF]

open access: yesarXiv, 2008
This paper is devoted to a study of linear, differential and topological classifications for linear controlled systems governed by ordinary differential equations. The necessary and sufficient conditions for the linear and topological equivalence are given. It is also shown that the differential equivalence is the same as the linear equivalence for the
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Boundary behaviors for linear systems of subsolutions of the stationary Schrödinger equation

open access: yesJournal of Inequalities and Applications, 2016
This paper investigates the boundary behaviors for linear systems of subsolutions of the stationary Schrödinger equation, which contain unstable subsystems.
Zongcai Jiang, Francisco Marco Usó
doaj   +1 more source

How Linear Is a Linear System?

open access: yes, 2019
Often, when testing structures, engineers assume the experimental system only exhibits linear behavior. This linear assumption means that the modal frequency and damping of the structure do not change with response level. In many assembled structures, components are connected through bolted joints. These systems behave in a weakly nonlinear fashion due
Benjamin R. Pacini   +2 more
openaire   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

On finite time delay dependent stability of linear discrete delay systems: Numerical solution approach [PDF]

open access: yesScientific Technical Review, 2015
In this paper, a possible solution of the basic nonlinear quadratic matrix equation was proposed. The solution is crucial in the formulation of the particular criteria for the delay-dependent finite time stability of discrete time delay systems ...
Debeljković Dragutin   +4 more
doaj  

Linear time logic control of linear systems with disturbances [PDF]

open access: yesarXiv, 2012
The formal analysis and design of control systems is one of recent trends in control theory. In this area, in order to reduce the complexity and scale of control systems, finite abstractions of control systems are introduced and explored. In non-disturbance case, the controller of control systems is often generated from the controller of finite ...
arxiv  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

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