Results 41 to 50 of about 16,970 (268)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Ultrasonic Planetary Core Drill: Overview and Results from Field Trial [PDF]

open access: yes, 2017
In the effort to explore the subsurface of terrestrial bodies, we seek to obtain better samples from ever greater depths. Many organisations are working towards technologies that can achieve this goal whilst ensuring compatibility with the likely ...
Harkness, Patrick   +4 more
core  

Synthesizing a Lego Forklift Controller in GR(1): A Case Study

open access: yes, 2016
Reactive synthesis is an automated procedure to obtain a correct-by-construction reactive system from a given specification. GR(1) is a well-known fragment of linear temporal logic (LTL) where synthesis is possible using a polynomial symbolic algorithm ...
Maoz, Shahar, Ringert, Jan Oliver
core   +2 more sources

Study of Rotary-Linear Ultrasonic Motor Output Shafts

open access: yesInternational Journal of Automation Technology, 2016
We propose output shafts with a preload generation mechanism to improve the output torque and thrust force of the rotary-linear ultrasonic motor. The stator is comprised of a single metallic cube with a through-hole, and the output shafts are inserted into the hole to generate motion in both its circumferential and axial directions arbitrarily. In this
Ayato Kanada   +2 more
openaire   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Robust position control of ultrasonic motor using VSS observer [PDF]

open access: yes, 2010
Intrinsic properties of ultrasonic motor (high torque for low speed, high static torque, compact in size, etc.) offer great advantages for industrial applications. However, when load torque is applied, dead-zone occurs in control input.
Darba, Araz   +4 more
core   +1 more source

Properties of piezoceramic materials in high electric field actuator applications

open access: yes, 2019
In this paper, we compare the performance of 8 PZT ceramics and one PMN-PT material for typical bending actuator applications. This includes the measurement of non-linear transverse charge coefficient at high electric field strength and related ...
Bruno, Binal P   +4 more
core   +1 more source

Ultrasonic Linear Motors Using Piezoelectric Actuators

open access: yesJournal of the Ceramic Society of Japan, 1988
A new type of linear motor using a piezoelectric actuator has been developed in which a mechanically resonating part slides on a stationary rail. The slider consists of two bimorphs, or a multilayered piezoelectric actuator with a bonded elastic vibratory fork.
Kenji UCHINO   +3 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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