Results 101 to 110 of about 905,622 (299)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Growth of covariant perturbations in the contracting phase of a bouncing universe
, 2012 In this paper we examine the validity of the linear perturbation theory near a bounce in the covariant analysis. Some linearity parameters are defined to set up conditions for a linear theory.
Atanu Kumar +3 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Electrical Tunability in 3-Gated Reconfigurable Transistor for Analog/RF Applications
IEEE Journal of the Electron Devices SocietyThe potential of electrical tunability in a 3-gated (3G) Reconfigurable Field Effect Transistor (RFET) for analog/RF applications is investigated through four distinct configurations (R ${}_{\text {2-IG-LVT}}$ , R ${}_{\text {1-IG-Ambi}}$ , R ${}_{\text {
Chinmayi Adoni +4 more
doaj +1 more source
The Flash ADC system and PMT waveform reconstruction for the Daya Bay Experiment
, 2018 To better understand the energy response of the Antineutrino Detector (AD), the Daya Bay Reactor Neutrino Experiment installed a full Flash ADC readout system on one AD that allowed for simultaneous data taking with the current readout system. This paper
Chang, Jinfan +14 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
MicromachinesGraded AlGaN channel High-Electron Mobility Transistor (HEMT) technology is emerging as a strong candidate for millimeter-wave applications, as superior efficiency and linearity performances can be achieved.
François Grandpierron +4 more
doaj +1 more source
, 2013 A recent paper by Kumar (2012) (hereafter K12) claimed that in a contracting model, described by perturbations around a collapsing Friedmann model containing dust or radiation, the perturbations can grow in such a way that the linearity conditions would ...
Pinto-Neto, N., Vitenti, S. D. P.
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source