Results 171 to 180 of about 58,035 (315)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Comparing Feedback Linearization and Jacobian Linearization for LQ Control of an Industrial Manipulator

, 2018
Feedback linearization is compared to Jacobian linearization for LQ control of atwo-link industrial manipulator. A method for obtaining equivalent nominal performance forboth control designs is introduced.
Moberg, Stig,, Hedberg, Erik,, Norrlöf, Mikael,, Gunnarsson, Svante,   +3 more
core  

Sunburn Prevalence Among US High School Students, Youth Risk Behavior Survey, United States, 2023. [PDF]

Prev Chronic Dis
Holman DM, Saelee R, Kiplagat SJ, Julian AK.   +3 more
europepmc   +1 more source

Linear Programming [PDF]

Operations Research, 1987
openaire   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A sliding-mode variable-structure controller based on exact feedback linearization for automatic navigation system

, 2016
In order to improve the path tracking accuracy and robustness of the agricultural machinery navigation system, a sliding-mode variable-structure controller based on exact feedback linearization was presented.
Bai XP(白晓平), Zhang T(张天), Hu JT(胡静涛), Gao L(高雷)   +3 more
core  

Implicit sub-stepping scheme for critical state soil models. [PDF]

Eng Comput
Bui HG, Niníc J, Meschke G.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Helicity of the bridge helix of Cas12a regulates on-target DNA cleavage efficiency and off-target cleavage propensity. [PDF]

Biochem Biophys Res Commun
Martin L, Rostami S, Schuster I, Qin PZ, Rajan R.   +4 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source