ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Physics-informed structural diagnostics of model-data agreement beyond scalar metrics. [PDF]
Haddadi H, Kloskowski A, Mironowicz P.
europepmc +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Estimating Motorcycle Telescopic Fork Suspension Travel Speed with Four-Degree-of-Freedom Full-Vehicle Kalman Filter. [PDF]
Ponso A, Pakštys S, Bonfitto A.
europepmc +1 more source
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Fast Numerical Solvers for Parameter Identification Problems in Mathematical Biology. [PDF]
Benková K, Pearson JW, Ptashnyk M.
europepmc +1 more source
An Inverse Generalized Conversion Filter for State Estimation in Nonlinear Adversarial Sensing Systems. [PDF]
Xi YA, Dong XH, Wu SY.
europepmc +1 more source
Machine learning-driven metastructure design for sensor-free linearization of MEMS electrothermal actuators. [PDF]
Zhang L +7 more
europepmc +1 more source
Lightweight hybrid neural network with physics consistency regularization for lithium-ion battery state of health estimation. [PDF]
Zhang P +4 more
europepmc +1 more source
Linearization routines for the parameter space concept to determine crystal structures without Fourier inversion. [PDF]
Vallinayagam M +3 more
europepmc +1 more source

