Results 61 to 70 of about 80,949 (337)

Simulation and Performance Analysis of MP-OLSR for Mobile Ad hoc Networks [PDF]

, 2008
Mobile ad hoc networks (MANETs) consist of a collection of wireless mobile nodes which dynamically exchange data without reliance on a fixed base station or a wired backbone network, which makes routing a crucial issue for the design of a ad hoc networks.
Cizeron, Eddy, Hamma, Salima, Parrein, Benoît, Yi, Jiazi   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analysis of OLSR Routing Protocol Performance Based on Gauss-Markov Mobility and Random Walk in Mobile Ad-Hoc Network (MANET)

JITeCS (Journal of Information Technology and Computer Science), 2023
MANET is included in the network without infrastructure from a collection of nodes that are interconnected to communicate. Routing protocol performance is a measure of the performance of how the ability of the routing protocol works.
Heru Nurwarsito, Ervani Sofyana Putra
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Performance Optimization of MANET Networks through Routing Protocol Analysis

Computers, 2020
A Mobile Ad Hoc Network (MANET) protocol requires proper settings to perform data transmission optimally. To overcome this problem, it is necessary to select the correct routing protocol and use the routing protocol’s default parameter values. This study
Tri Kuntoro Priyambodo, Danur Wijayanto, Made Santo Gitakarma   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Lightweight Routing Protocol for Named Data Networking [PDF]

Jisuanji kexue yu tansuo
Named data networking (NDN) is a novel network architecture that revolves around information-centric principles. In order to acquire global routing information within the network, typical NDN routing protocols rely on data synchronization mechanisms to ...
ZOU Bowen, SONG Tian, LI Tianlong, YANG Yating
doaj   +1 more source

Analisis Distance Vector Protocol Routing dan Link State Routing Protocol Pada Jaringan Software Defined Network

Jurnal Repositor, 2020
Dengan semakin berkembangnya jaringan computer, skalabilitas, dan kompleksitas jaringan pun semakin tinggi. Hal ini menimbulkan permasalahan pada jaringan konvensional yang salah satunya adalah konfigurasi yang dilakukan semakin kompleks. Teknologi SDN dengan memberikan solusi dalam mengelola, merancangan, serta membangun jaringan dengan memisahkan ...
Pratiwi, Dwi Nurmasari, Faiqurahman, Mahar, Akbi, Denar Regata   +2 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source