Results 111 to 120 of about 222,218 (196)

Correction: Long-term evaluation of the success rate of different treatment modalities on MIH-affected teeth. [PDF]

Eur Arch Paediatr Dent
Seremidi K, Petroleka K, Kraemer N, Gizani S.   +3 more
europepmc   +1 more source

Adaptive Evolution in Linked Genomes

, 2011
Adaptive evolution is governed by various forces: Mutations occur randomly in the genome and generate variability in the individuals’reproductive success; natural selection shifts this variability in the population towards individuals with high fitness; genetic drift introduces random fluctuations in the number of offspring of an individual and affects
openaire   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Editorial: Life under pressure: microbial adaptation and survival in high pressure environments. [PDF]

Front Microbiol
Jebbar M, Li XG.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Wellness4Students Program to Mitigate Stress, Anxiety, and Depression Among Makerere University Students in Uganda: Protocol for a Longitudinal Study.

JMIR Res Protoc
Wandera SO, Nankinga O, Ndugga P, Namugenyi C, Ashaba C, Nakasujja N, Kasujja R, Agyapong B, Agyapong VIO.   +8 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Reinforcement drives within- not between-trial motor adaptation. [PDF]

Sci Rep
Lehnberg FM, Paul T, Wiemer VM, Grafton ST, Fink GR, Volz LJ.   +5 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Is MELD-Na Truly Predictive of Diuretic Response in Heart Failure? Methodological and Physiological Considerations. [PDF]

Clin Cardiol
Chaman Lal K, Fatima M, Soomro S, Siddiqui A.   +3 more
europepmc   +1 more source