Results 121 to 130 of about 173,497 (273)

Video Quality Prediction Models Based on Video Content Dynamics for H.264 Video over UMTS Networks

open access: yesInternational Journal of Digital Multimedia Broadcasting, 2010
The aim of this paper is to present video quality prediction models for objective non-intrusive, prediction of H.264 encoded video for all content types combining parameters both in the physical and application layer over Universal Mobile ...
Asiya Khan   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Restricting the Spurious Growth of Knowledge Graphs by Using Ontology Graphs

open access: yesIEEE Access
Knowledge Graphs have demonstrated a real advantage in knowledge representation, leveraging graphs NoSQL structures and schema-less technology, which offers superior comprehension, knowledge representation, interpretation, and reasoning.
Kina Tatchukova, Yanzhen Qu
doaj   +1 more source

Link prediction based on directed network clustering coefficient.

open access: yes, 2019
In this paper we analyse network link prediction methods based on a concept of digraph clustering coefficient proposed by M. Bloznelis and L. Leskelä.
Verseckas, Žilvinas,
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Explicit and Implicit Feature Contrastive Learning Model for Knowledge Graph Link Prediction

open access: yesSensors
Knowledge graph link prediction is crucial for constructing triples in knowledge graphs, which aim to infer whether there is a relation between the entities.
Xu Yuan   +5 more
doaj   +1 more source

Improving Link Ranking Quality by Quasi-Common Neighbourhood

open access: yes, 2015
Most of the best performing link prediction ranking measures evaluate the common neighbourhood of a pair of nodes in a network, in order to assess the likelihood of a new link.
Milani, Alfredo   +7 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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