Results 281 to 290 of about 537,873 (344)

Causal Relationships Between Gastroesophageal Reflux Disease and Myocardial Infarction: Insights From Univariable and Multivariable Mendelian Randomization Analyses

Annals of Human Genetics, EarlyView.
ABSTRACT Background Observational studies have indicated that gastroesophageal reflux disease (GERD) is connected to myocardial infarction (MI). Nonetheless, the question of causality in these relationships remains unresolved, given the potential influence of confounding variables.
Xiaoya Zheng, Teng Hu, Tianxiang Fang, Pengpeng Su, Yingsong Wang, Ning Huangfu   +5 more
wiley   +1 more source

Linkage disequilibrium and phylogenetic congruence between chloroplast and mitochondrial haplotypes inSilene vulgaris

, 2000
Matthew S. Olson, David E. McCauley
openalex   +2 more sources

The History of the Panmictic Population Concept and Its Legacy in Contemporary Population Genetics

Annals of Human Genetics, EarlyView.
ABSTRACT The panmictic population concept is at the heart of population, evolutionary and conservation genetics. However, in nature, true panmictic populations are vanishingly rare. As an idea conceived for modelling evolutionary dynamics, it has been thought that the assumption of panmixia was formalised during the development of the Modern Synthesis.
Andy Walton, Alex Aylward, Mark G. Thomas, Adam Rutherford   +3 more
wiley   +1 more source

The Effect of Linkage Disequilibrium and Family Relationships on the Reliability of Genomic Prediction

Genetics, 2013
Y. Wientjes, R. Veerkamp, M. Calus
semanticscholar   +1 more source

Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies

Allergy, EarlyView.
Atopic eczema is a complex trait resulting from multiple genetic and environmental factors. This study investigated evidence for interaction between 24 established eczema genetic risk variants and 18 environmental factors. One variant‐environmental pair showed nominally significant interaction in discovery, replication and meta‐analyses: early‐life dog
Marie Standl, Ashley Budu‐Aggrey, Luke J. Johnston, Martina S. Elias, S. Hasan Arshad, Peter Bager, Veronique Bataille, Helena Blakeway, Klaus Bønnelykke, Dorret Boomsma, Ben M. Brumpton, Mariona Bustamante Pineda, Archie Campbell, John A. Curtin, Anders Eliasen, João P. S. Fadista, Bjarke Feenstra, Trine Gerner, Carolina Medina‐Gomez, Sarah Grosche, Kristine B. Gutzkow, Anne‐Sofie Halling, Caroline Hayward, John Henderson, Esther Herrera‐Luis, John W. Holloway, Joukejan Hottenga, Jonathan O’B Hourihane, Chen Hu, Kristian Hveem, Amaia Irizar, Bénédicte Jacquemin, Leon Jessen, Sara Kress, Ramesh J. Kurukulaaratchy, Susanne Lau, Sabrina Llop, Mari Løset, Ingo Marenholz, Dan Mason, Daniel L. McCartney, Mads Melbye, Erik Melén, Camelia Minica, Clare S. Murray, Tamar Nijsten, Luba M. Pardo, Suzanne Pasmans, Craig E. Pennell, Maria R. Rinnov, Gillian Santorelli, Tamara Schikowski, Darina Sheehan, Angela Simpson, Cilla Söderhäll, Laurent F. Thomas, Jacob P. Thyssen, Maties Torrent, Toos van Beijsterveldt, Alessia Visconti, Judith M. Vonk, Carol A. Wang, Cheng‐Jian Xu, Ali H. Ziyab, UK Translational Research Network in Dermatology, BIOMAP Consortium, Adnan Custovic, Paola Di Meglio, Liesbeth Duijts, Carsten Flohr, Alan D. Irvine, Gerard H. Koppelman, Young‐Ae Lee, Nick J. Reynolds, Catherine Smith, Sinéad M. Langan, Lavinia Paternoster, Sara J. Brown   +77 more
wiley   +1 more source

Battle in the Clouds

American Anthropologist, EarlyView.
ABSTRACT This narrative experiment brings together scenes from my family histories in western Pennsylvania coal country, alongside ongoing visits to learn about rising health issues in the region today. Increasing numbers of residents express concerns about chronic problems such as young cancers, and many people worry about potential exposures coming ...
Amy Moran‐Thomas
wiley   +1 more source

GAUSS: a summary-statistics-based R package for accurate estimation of linkage disequilibrium for variants, Gaussian imputation, and TWAS analysis of cosmopolitan cohorts. [PDF]

Bioinformatics
Lee D, Bacanu SA.
europepmc   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Long‐term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
FinnGen data of 213 942 women was utilized in order to investigate the risk of cardiovascular disease in women with and without hypertensive disorders of pregnancy and with diverse genetic risks for cardiovascular disease and preeclampsia measured with polygenic risk scores.
Anna Kivioja, Jaakko Tyrmi, Elli Toivonen, Heini Huhtala, FinnGen, Tiina Jääskeläinen, Johannes Kettunen, Tanja Saarela, Hannele Laivuori   +8 more
wiley   +1 more source

Comparative assessment of the effective population size and linkage disequilibrium of Karan Fries cattle revealed viable population dynamics. [PDF]

Anim Biosci
Bhardwaj S, Togla O, Mumtaz S, Yadav N, Tiwari J, Muansangi L, Illa SK, Wani YM, Mukherjee S, Mukherjee A.   +9 more
europepmc   +1 more source