Results 291 to 300 of about 537,873 (344)

Structure of linkage disequilibrium and phenotypic associations in the maize genome

open access: green, 2001
David L. Remington   +8 more
openalex   +1 more source

Macau as Method: Recombinant Urbanism in Post‐Socialist China

open access: yesAsia Pacific Viewpoint, EarlyView.
ABSTRACT In ‘Asia as Method’, Chen Kuan‐Hsing argues for the value of an indigenous inter‐Asian approach to analysing the effects of European imperialism on the countries and citizens of Asia. This article mobilises both Chen's inter‐Asian referencing strategy and the city‐state of Macau to explore Macau's role in China's engagements with global ...
Tim Simpson
wiley   +1 more source

Real‐world clinical experience with NGS‐based chimerism analyses in haematopoietic stem cell transplant patients

open access: yesBritish Journal of Haematology, EarlyView.
This study demonstrates the clinical utility of a next‐generation sequencing (NGS)‐based chimerism assay (CASAL) in haematopoietic stem cell transplantation (HSCT). Compared to conventional short tandem repeat (STR) methods, CASAL showed significantly higher marker informativeness, detecting mixed chimerism (MC) below 5% recipient DNA with a median of ...
Jin Ju Kim   +7 more
wiley   +1 more source

Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Chemotherapeutic treatment for colorectal cancer (colorectal cancer) allows for increased patient overall survival. However, current therapeutic regimens are often associated with the development of adverse drug reactions, which represent a morbidity, mortality and economic issue.
Ana Rita Simoes   +20 more
wiley   +1 more source

A Genomewide Linkage-Disequilibrium Scan Localizes the Saguenay–Lac-Saint-Jean Cytochrome Oxidase Deficiency to 2p16

open access: bronze, 2001
Nana Lee   +9 more
openalex   +1 more source

Genetic Association of Primary Angle‐Closure Glaucoma and Disease Progression

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate single‐nucleotide polymorphisms (SNPs) reported in the largest up‐to‐date systematic review and meta‐analysis on primary angle‐closure disease (PACD), on their associations with primary angle‐closure glaucoma (PACG) and disease progression.
Yu Jing Liang   +6 more
wiley   +1 more source

Military‐Connected Adolescents' Coping Strategies and Psychological Well‐Being: The Moderating Role of Family Functioning

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Military‐connected adolescents face unique challenges associated with military life, and some coping strategies are more beneficial to their well‐being than others. It is important to understand their use of various coping strategies in connection with their psychological well‐being and if there are family circumstances in which these coping ...
Meredith L. Farnsworth   +1 more
wiley   +1 more source

The Phenotypic Spectrum of Miller Syndrome: Insight From a French Cohort

open access: yesClinical Genetics, EarlyView.
This study expands the clinical spectrum of Miller syndrome by reporting novel features including preaxial defects, facial nevus simplex, and optic atrophy. It also includes the first patients with homozygous DHODH variants, emphasizing the importance of early diagnosis and the variability of presentations, from severe prenatal to mild adult phenotypes.
Marion Aubert Mucca   +13 more
wiley   +1 more source

Targeting FABP4 to Inhibit AGEs‐RAGE/NF‐κB Signalling Effectively Ameliorates Nucleus Pulposus Dysfunction and Angiogenesis in Obesity‐Related Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Obesity promotes the progression of intervertebral disc degeneration (IVDD) through the mTORC1/FABP4 axis. Targeting FABP4 effectively ameliorates nucleus pulposus dysfunction and angiogenesis in obesity‐related IVDD. ABSTRACT Intervertebral disc degeneration (IVDD) is a primary contributor to low back pain, posing significant social and economic ...
Lin Han   +8 more
wiley   +1 more source

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