Results 91 to 100 of about 3,690,639 (348)

A saturated genetic linkage map of autotetraploid alfalfa (Medicago sativa L.) developed using genotyping-by-sequencing is highly syntenous with the Medicago truncatula genome. [PDF]

, 2014
A genetic linkage map is a valuable tool for quantitative trait locus mapping, map-based gene cloning, comparative mapping, and whole-genome assembly. Alfalfa, one of the most important forage crops in the world, is autotetraploid, allogamous, and highly
Acharya, Ananta, Brummer, E Charles, Jiang, Qingzhen, Kang, Junmei, Li, Xuehui, Wei, Yanling   +5 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

DLforum – A multidisciplinary online discussion forum for data linkage researchers and practitioners

International Journal of Population Data Science, 2018
Data linkage, the process of identifying records that refer to the same entities across databases, is a crucial component of Population Data Science. Data linkage has a history going back over fifty years with many different methods and techniques being ...
Peter Christen, Thilina Ranbaduge, Dinusha Vatsalan   +2 more
doaj   +1 more source

Location of chlorogenic acid biosynthesis pathway and polyphenol oxidase genes in a new interspecific anchored linkage map of eggplant [PDF]

, 2014
© Gramazio et al.; licensee BioMed Central. 2014. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Bombarely, A Cho, A Concellón, A Frary, A Kumar, A Moglia, A Stàgel, AP Singh, B Menin, BD Whitaker, C Chai, C Coetzer, C Comino, C Comino, C Ma, C Urbany, CM André, CM Rommens, D Chagné, D Kosambi, D Luthria, E Portis, E Portis, E Portis, EC Ramirez, Elena Castillo, F Wu, F Wu, Francisco Javier Herraiz, G Mennella, H Fukuoka, H Fukuoka, Isabel Andújar, J Doyle, J Prohens, J Prohens, J Van Ooijen, Jaime Prohens, JR Stommel, K Shirasawa, K Yamakawa, KV Alheit, L Barchi, L Barchi, L Barchi, L Tran, M Di Guardo, M Doğan, M Jeuken, M Krzywinski, M Murata, M Plazas, M Plazas, Mariola Plazas, MC Daunay, MD Dos Santos, MD Raigón, P Byrne, P Vos, Pietro Gramazio, PM Hanson, R Kofler, R Lo Scalzo, R Niggeweg, R Shi, Rachel S Meyer, RN Lester, S Doganlar, S Doganlar, S Knapp, S Rozen, S Vilanova, Sandra Knapp, Santiago Vilanova, SM Newman, SM Shetty, T Nunome, T Nunome, T Nunome, T Vogt, TA Hall, The Angiosperm Phylogeny Group, TM Fulton, Y Ren, Z Huang   +84 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Going open source: some lessons learned from the development of OpenRecLink

Cadernos de Saúde Pública, 2015
Record linkage is the process of identifying and merging records across different databases belonging to the same entity. The health sector is one of the pioneering areas of record linkage techniques applications.
Kenneth Rochel de Camargo Jr., Claudia Medina Coeli   +1 more
doaj   +1 more source

Advanced nonlinear modelling techniques for switched reluctance machines [PDF]

, 2003
This paper gives an overview of different modelling techniques to describe the nonlinear behaviour of both saturated switched reluctance machine (SRM) and power electronic converter.
Belmans, Ronnie, D'Hulster, Frederik, Desmet, Jan, Stockman, Kurt   +3 more
core  

Development and characterization of tri- and tetra-nucleotide polymorphic microsatellite markers for skipjack tuna (Katsuwonus pelamis) [PDF]

, 2012
Skipjack tuna (katsuwonus pelamis) (SJT) is the largest tuna fishery in all the major oceans around the world, and the largest marine fishery in Sri Lanka. Knowledge of genetic population structure and effective population size of SJT in the Indian Ocean
Chand, Vincent, Dammannagoda Acharige, Sudath, Mather, Peter   +2 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

AWclust: point-and-click software for non-parametric population structure analysis

BMC Bioinformatics, 2008
Background Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STRUCTURE and L-POP, usually assume Hardy-Weinberg equilibrium (HWE) and linkage equilibrium among loci in ...
Starmer Joshua D, Gao Xiaoyi
doaj   +1 more source