Results 91 to 100 of about 565,196 (323)

Using linkage maps to correct and scaffold de novo genome assemblies: Methods, challenges and computational tools

open access: yesFrontiers in Genetics, 2015
Modern high-throughput DNA sequencing has made it possible to inexpensively produce genome sequences, but in practice many of these draft genomes are fragmented and incomplete.
Janna Lynn Fierst
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

From Probabilistic to Fuzzy Matching Record Linkage: A promising Transition

open access: yesInternational Journal of Population Data Science
Objective Probabilistic Record Linkage (PRL) heavily relies on manual intervention for gray area resolutions. This makes PRL extremely time and resource intensive. No matter how scientifically sound and robust PRL method is, it didn’t meet close-to-real-
Mahmoud Azimaee   +4 more
doaj   +1 more source

Hierarchical Cluster Analysis: Comparison of Three Linkage Measures and Application to Psychological Data [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2015
Cluster analysis refers to a class of data reduction methods used for sorting cases, observations, or variables of a given dataset into homogeneous groups that differ from each other.
Odilia Yim, Kylee T. Ramdeen
doaj  

netgwas: An R Package for Network-Based Genome-Wide Association Studies

open access: yes, 2019
Graphical models are powerful tools for modeling and making statistical inferences regarding complex associations among variables in multivariate data.
Arends, Danny   +2 more
core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Evaluating PPRL Vs Clear Text Linkage with Real-World Data

open access: yesInternational Journal of Population Data Science, 2020
Introduction Privacy-preserving Record Linkage (PPRL) is a record linkage technique that can increase the security of personal information. PPRL uses techniques of either hashing identifiers (where exact matches are required) or Blooming identifiers ...
Michael Jarrett   +7 more
doaj   +1 more source

Coupling CFD and visualisation to model the behaviour and effect on visibility of small particles in air [PDF]

open access: yes, 2004
The use of computational fluid dynamics (CFD) and lighting simulation software is becoming commonplace in building design. This study looks at a novel linkage between these two tools in the visualization of droplets or particles suspended in air.
Kelly, Nick, Macdonald, Iain
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

OPTIMASI DESAIN MEKANISME LINKAGE GUIDE VANE UNTUK PENGATURAN ALIRAN MASUK AIR KE SUDU PADA TURBIN BANKI

open access: yesJurnal Teknik Pertanian Lampung, 2020
Salah satu bagian penting dalam turbin banki adalah pengaturan guide vane, karena aliran masuk air ke sudu pada turbin tergantung dari pengaturan guide vane nya, baik pada debit rendah maupun normal.
Sirojuddin   +2 more
doaj   +1 more source

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