Results 101 to 110 of about 604,743 (325)

Hierarchical Cluster Analysis: Comparison of Three Linkage Measures and Application to Psychological Data [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2015
Cluster analysis refers to a class of data reduction methods used for sorting cases, observations, or variables of a given dataset into homogeneous groups that differ from each other.
Odilia Yim, Kylee T. Ramdeen
doaj  

A Novel DNA Repair Disorder With Thrombocytopenia, Nephrosis, and Features Overlapping Cockayne Syndrome [PDF]

open access: yes, 2009
We report on four siblings with Cockayne-like syndrome with thrombocytopenia and nephrotic syndrome. The parents were healthy and consanguineous, consistent with an autosomal recessive mode of disease inheritance.
Cockayne   +11 more
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

X-LDR: an atlas of linkage disequilibrium across species

open access: yesGenome Biology
To reach a genomic scale illustration for linkage disequilibrium (LD), we introduce X-LDR, a stochastic algorithm for biobank-scale data ( $$\mathcal {O}(nmB)$$ , n the sample size, m the number of SNPs, and B iterations).
Tian-Neng Zhu   +12 more
doaj   +1 more source

Evaluating PPRL Vs Clear Text Linkage with Real-World Data

open access: yesInternational Journal of Population Data Science, 2020
Introduction Privacy-preserving Record Linkage (PPRL) is a record linkage technique that can increase the security of personal information. PPRL uses techniques of either hashing identifiers (where exact matches are required) or Blooming identifiers ...
Michael Jarrett   +7 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

OPTIMASI DESAIN MEKANISME LINKAGE GUIDE VANE UNTUK PENGATURAN ALIRAN MASUK AIR KE SUDU PADA TURBIN BANKI

open access: yesJurnal Teknik Pertanian Lampung, 2020
Salah satu bagian penting dalam turbin banki adalah pengaturan guide vane, karena aliran masuk air ke sudu pada turbin tergantung dari pengaturan guide vane nya, baik pada debit rendah maupun normal.
Sirojuddin   +2 more
doaj   +1 more source

R Package ASMap: Efficient Genetic Linkage Map Construction and Diagnosis

open access: yesJournal of Statistical Software, 2017
Although various forms of linkage map construction software are widely available, there is a distinct lack of packages for use in the R statistical computing environment (R Core Team 2017).
Julian Taylor, David Butler
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A High-density linkage map for Eucalyptus urophylla and E. grandis based on 1,100 F1 progenies genotyped with 6,000 SnP markers : P0474 [PDF]

open access: yes, 2013
Next generation sequencing (NGS) technologies and high-throughput genotyping methods offer the possibility to produce dense linkage maps with highly reliable markers which can be anchored on the physical map of the genome.
Bartholomé, Jérôme   +5 more
core  

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