Results 111 to 120 of about 3,690,639 (348)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

X-LDR: an atlas of linkage disequilibrium across species

Genome Biology
To reach a genomic scale illustration for linkage disequilibrium (LD), we introduce X-LDR, a stochastic algorithm for biobank-scale data ( $$\mathcal {O}(nmB)$$ , n the sample size, m the number of SNPs, and B iterations).
Tian-Neng Zhu, Xing Huang, Meng-Yuan Yang, Guo-An Qi, Qi-Xin Zhang, Feng Lin, Wenjing Zhang, Zhe Zhang, Xin Jin, Hou-Feng Zheng, Hai-Ming Xu, Shizhou Yu, Guo-Bo Chen   +12 more
doaj   +1 more source

From Probabilistic to Fuzzy Matching Record Linkage: A promising Transition

International Journal of Population Data Science
Objective Probabilistic Record Linkage (PRL) heavily relies on manual intervention for gray area resolutions. This makes PRL extremely time and resource intensive. No matter how scientifically sound and robust PRL method is, it didn’t meet close-to-real-
Mahmoud Azimaee, Gangamma Kalappa, Charlotte Ma, Nan Wang, Winnie Shen   +4 more
doaj   +1 more source

Hierarchical Cluster Analysis: Comparison of Three Linkage Measures and Application to Psychological Data [PDF]

Tutorials in Quantitative Methods for Psychology, 2015
Cluster analysis refers to a class of data reduction methods used for sorting cases, observations, or variables of a given dataset into homogeneous groups that differ from each other.
Odilia Yim, Kylee T. Ramdeen
doaj  

Evaluating PPRL Vs Clear Text Linkage with Real-World Data

International Journal of Population Data Science, 2020
Introduction Privacy-preserving Record Linkage (PPRL) is a record linkage technique that can increase the security of personal information. PPRL uses techniques of either hashing identifiers (where exact matches are required) or Blooming identifiers ...
Michael Jarrett, Brent Hills, Yinshan Zhao, Adrian Brown, Sean Randall, James Boyd, Anna Ferrante, Kimberlyn McGrail   +7 more
doaj   +1 more source

A High-density linkage map for Eucalyptus urophylla and E. grandis based on 1,100 F1 progenies genotyped with 6,000 SnP markers : P0474 [PDF]

, 2013
Next generation sequencing (NGS) technologies and high-throughput genotyping methods offer the possibility to produce dense linkage maps with highly reliable markers which can be anchored on the physical map of the genome.
Bartholomé, Jérôme, Gion, Jean-Marc, Klopp, Christophe, Mandrou, Eric, Nabihoudine, Ibouniyamine, Plomion, Christophe   +5 more
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

OPTIMASI DESAIN MEKANISME LINKAGE GUIDE VANE UNTUK PENGATURAN ALIRAN MASUK AIR KE SUDU PADA TURBIN BANKI

Jurnal Teknik Pertanian Lampung, 2020
Salah satu bagian penting dalam turbin banki adalah pengaturan guide vane, karena aliran masuk air ke sudu pada turbin tergantung dari pengaturan guide vane nya, baik pada debit rendah maupun normal.
Sirojuddin, Ahmad Kholil, Prima Chandra Utama   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

PRSice: Polygenic Risk Score software

Bioinform., 2014
Summary: A polygenic risk score (PRS) is a sum of trait-associated alleles across many genetic loci, typically weighted by effect sizes estimated from a genome-wide association study.
J. Euesden, C. Lewis, P. O’Reilly
semanticscholar   +1 more source