Results 111 to 120 of about 588,273 (328)
NASTRAN as a resource in code development [PDF]
, 1975 A case history is presented in which the NASTRAN system provided both guidelines and working software for use in the development of a discrete element program, PATCHES-111.
Crain, L. M., Neu, T. F., Stanton, E. L.
core +1 more source
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study [PDF]
, 2005 Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability.
Bukulmez, H +9 more
core +2 more sources
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Record-Linkage from a Technical Point of View [PDF]
TRecord linkage is used for preparing sampling frames, deduplication of lists and combining information on the same object from two different databases.
Rainer Schnell
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
An integrated genomic approach for the study of mandibular prognathism in the European seabass (Dicentrarchus labrax) [PDF]
, 2016 Skeletal anomalies in farmed fish are a relevant issue affecting animal welfare and health and causing significant economic losses. Here, a high-density genetic map of European seabass for QTL mapping of jaw deformity was constructed and a genome-wide ...
Babbucci, Massimiliano +7 more
core +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
A method and a tool for geocoding and record linkage [PDF]
For many years, researchers have presented the geocoding of postal addresses as a challenge. Several research works have been devoted to achieve the geocoding process.
CHARIF Omar +4 more
core +1 more source
Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain [PDF]
, 2011 Objectives: The thickness of the brain’s cortical gray matter (GM) and the fractional anisotropy (FA) of the cerebral white matter (WM) each follow an inverted U-shape trajectory with age. The two measures are positively correlated and may be modulated
Anderson eWinkler +18 more
core +5 more sources