Results 131 to 140 of about 601,196 (298)
Genome-Wide Association and Linkage Analysis of Quantitative Traits: Comparison pf Likelihood-Ratio Test and Conditional Score Statistic [PDF]
, 2009 Over the past decade, genetic analysis has shifted from linkage studies, which identify broad regions containing putative trait loci, to genome-wide association studies, which detect the association of a marker with a specific phenotype.
Dupuis, Josée +2 more
core +1 more source
MapChart: Software for the Graphical Presentation of Linkage Maps and QTLs [PDF]
, 2002 Roeland E. Voorrips
openalex +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Exploration of flowering control in Lolium perenne L. [PDF]
, 2009 End of project reportFlowering or heading in Lolium perenne (perennial ryegrass) is induced by a period of vernalization, followed by long days at higher temperatures.
Byrne, Stephen +3 more
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Exploiting Persistent Linkage in Software Engineering Environments [PDF]
, 1995 Ron Morrison +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Satellite freeze forecast system [PDF]
Provisions for back-up operations for the satellite freeze forecast system are discussed including software and hardware maintenance and DS/1000-1V linkage; troubleshooting; and digitized radar usage.
Martsolf, J. D.
core +1 more source
Identification of Quantitative Trait Loci Determining Vegetative Growth Traits in Coffea Canephor [PDF]
, 2011 Recently the use of molecular markers has been successfully applied for some crops. For coffee, new opportunities have been opened since Nestlé R&D Centre in collaboration with ICCRI completed the first genetic map of Coffea canephora. This study was
Crouzillat, C. (Crouzillat) +2 more
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