Results 71 to 80 of about 273,241 (304)

Multi-objective Test Case Selection Through Linkage Learning-based Crossover [PDF]

13th Symposium on Search-Based Software Engineering (SSBSE) 2021, 2021
Test Case Selection (TCS) aims to select a subset of the test suite to run for regression testing. The selection is typically based on past coverage and execution cost data. Researchers have successfully used multi-objective evolutionary algorithms (MOEAs), such as NSGA-II and its variants, to solve this problem.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Going open source: some lessons learned from the development of OpenRecLink

Cadernos de Saúde Pública, 2015
Record linkage is the process of identifying and merging records across different databases belonging to the same entity. The health sector is one of the pioneering areas of record linkage techniques applications.
Kenneth Rochel de Camargo Jr., Claudia Medina Coeli   +1 more
doaj   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

AWclust: point-and-click software for non-parametric population structure analysis

BMC Bioinformatics, 2008
Background Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STRUCTURE and L-POP, usually assume Hardy-Weinberg equilibrium (HWE) and linkage equilibrium among loci in ...
Starmer Joshua D, Gao Xiaoyi
doaj   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Linkage analysis and integrated software GAPL for pure-line populations derived from four-way and eight-way crosses

Crop Journal, 2019
Pure lines derived from multiple parents provide abundant variation for genetic study. However, efficient genetic analysis methods and user-friendly software are still lacking.
Luyan Zhang, Lei Meng, Jiankang Wang
doaj  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Building a high quality data linkage spine using a targeted approach to clerical review

International Journal of Population Data Science, 2017
Objectives The Tasmanian Data Linkage Unit (TDLU) was established through the University of Tasmania in 2011 with the first dataset imported to its Master Linkage Map (MLM) during 2014.
Nadine Wiggins, Brian Stokes
doaj   +1 more source

Increasing Transparent and Accountable Use of Data by Quantifying the Actual Privacy Risk in Interactive Record Linkage [PDF]

arXiv, 2019
Record linkage refers to the task of integrating data from two or more databases without a common identifier. MINDFIRL (MInimum Necessary Disclosure For Interactive Record Linkage) is a software system that demonstrates the tradeoff between utility and privacy in interactive record linkage. Due to the need to access personally identifiable information (
arxiv